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〒222-0036 神奈川県横浜市港北区小机町3302-5(日産スタジアム内)

内科(循環器)internal medicine (Cardiology)

学術実績(主な研究論文)

2013年

Alterations in echocardiographic and electrocardiographic features in Japanese professional soccer players: comparison to African-Caucasian ethnicities.

Kervio G, Pelliccia A, Nagashima J, Wilson MG, Gauthier J, Murayama M, Uzan L, Ville N, Carre F.
Eur J Prev Cardiol. 2013 Oct;20(5):880-8. doi: 10.1177/2047487312447905. Epub 2012 May 1.
2011年

Dynamic component of sports is an important determinant factor of heart rate recovery.

Nagashima J, Matsumoto N, Takagi A, Musha H, Chikaraishi K, Sagehashi M, Nakagawa R, Ishige N, Fujimaki R, Akaike A, Seo R, Aoki H, Murayama M.
J Cardiol. 2011 Sep;58(2):191-6. Epub 2011 Jun 21.
2010年

Three-month exercise and weight loss program improves heart rate recovery in obese persons along with cardiopulmonary function.

Nagashima J, Musha H, Takada H, Takagi K, Mita T, Mochida T, Yoshihisa T, Imagawa Y, Matsumoto N, Ishige N, Fujimaki R, Nakajima H, Murayama M.
J Cardiol. 2010 Jul;56(1):79-84. Epub 2010 Apr 7.

A novel microsatellite polymorphism of sodium channel beta1-subunit gene (SCN1B) may underlie abnormal cardiac excitation manifested by coved-type ST-elevation compatible with Brugada syndrome in Japanese.

Ogawa R, Kishi R, Takagi A, Sakaue I, Takahashi H, Matsumoto N, Masuhara K, Nakazawa K, Kobayashi S, Miyake F, Echizen H.
Int J Clin Pharmacol Ther. 2010 Feb;48(2):109-19.
2007年

Influence of physical fitness and smoking on the coagulation system in hypertensive patients: effect on prothrombin fragment F1+2.

Nagashima J, Musha H, Takada H, Matsumoto N, Fujimaki R, Ishige N, Aono J, Murayama M.
Intern Med. 2007;46(13):933-6. Epub 2007 Jul 2.

Discrimination of Brugada syndrome patients from individuals with the saddle-back type ST-segment elevation using a marker of the standard 12-lead electrocardiography.

Nakazawa K, Sakurai T, Kishi R, Takagi A, Osada K, Ryu S, Fujita S, Matsuda H, Ishikawa Y, Miyake F.
Circ J. 2007 Apr;71(4):546-9.
2006年

Left ventricular chamber size predicts the race time of Japanese participants in a 100 km ultramarathon.

Nagashima J, Musha H, Takada H, Murayama M.
Br J Sports Med. 2006 Apr;40(4):331-3; discussion 333.

Population pharmacokinetic and pharmacodynamic analysis of a class IC antiarrhythmic, pilsicainide, in patients with cardiac arrhythmias.

Ogawa R, Kishi R, Mihara K, Takahashi H, Takagi A, Matsumoto N, Masuhara K, Nakazawa K, Miyake F, Kobayashi S, Echizen H.
J Clin Pharmacol. 2006 Jan;46(1):59-68.
2005年

Long-term follow-up of a patient with Kawasaki disease and coronary aneurysm associated with asymptomatic thrombosis: a case report.

Matsuda H, Hashimoto N, Suzuki K, Aoyagi H, Akashi Y, Kawasaki K, Tsuchiya K, Ozawa A, Nagashima J, Musha H.
J Cardiol. 2005 Sep;46(3):113-8.
2004年

Clinical significance of electrocardiography recordings from a higher intercostal space for detection of the brugada sign.

Nakazawa K, Sakurai T, Takagi A, Kishi R, Osada K, Miyazu O, Watanabe Y, Miyake F.
Circ J. 2004 Nov;68(11):1018-22.

New holter monitoring analysis system: a calculation of the lead vectors.

Nanke T, Nakazawa K, Sakurai T, Matsumoto N, Kishi R, Takagi A, Sato C, Miyake F, Yamaki T, Kaneko M.
Circ J. 2004 Aug;68(8):751-6.

Brugada syndrome-like ST-segment elevation increase exacerbated by vomiting.

Arai M, Nakazawa K, Takagi A, Kishi R, Osada K, Ryu S, Miyake F.
Circ J. 2004 Jul;68(7):712-4.

Efficacy of steroid therapy for pacing failure in a patient with chronic myocarditis.

Mitsuya N, Kishi R, Suzuki N, Tamura M, Imai Y, Tanaka O, Takagi A, Nakazawa K, Miyake F, Nobuoka S, Koike J.
Intern Med. 2004 Mar;43(3):213-7.

Congenital absence of the left circumflex coronary artery associated with acute myocardial infarction: a case report.

Hashimoto N, Nagashima J, Miyazu O, Akashi Y, Kawasaki K, Imai Y, Tsuchiya K, Ozawa A, So T, Musha H, Sakakibara M, Miyake F.
Circ J. 2004 Jan;68(1):91-3.
2003年

New upper limit of physiologic cardiac hypertrophy in Japanese participants in the 100-km ultramarathon.

Nagashima J, Musha H, Takada H, Murayama M.
J Am Coll Cardiol. 2003 Nov 5;42(9):1617-23.

Autonomic imbalance as a property of symptomatic Brugada syndrome.

Nakazawa K, Sakurai T, Takagi A, Kishi R, Osada K, Nanke T, Miyake F, Matsumoto N, Kobayashi S.
Circ J. 2003 Jun;67(6):511-4.

Reversible ventricular dysfunction (takotsubo cardiomyopathy) following polymorphic ventricular tachycardia.

Akashi YJ, Nakazawa K, Kida K, Ryu S, Takagi A, Kishi R, Kunishima T, Sakakibara M, Miyake F.
Can J Cardiol. 2003 Mar 31;19(4):449-51.

Influence of mobile magnetic resonance imaging on implanted pacemakers.

Kishi R, Matsumoto N, Nakazawa K, Takagi A, Sakurai T, Nanke T, Watanabe Y, Miyazu O, Harada T, Kobayashi S, Miyake F.
Pacing Clin Electrophysiol. 2003 Jan;26(1 Pt 2):527-9.
2002年

Prolongation of LAS40 (duration of the low amplitude electric potential component (<40 microV) of the terminal portion of the QRS) induced by isoproterenol in 11 patients with Brugada syndrome.

Takagi A, Nakazawa K, Sakurai T, Nanke T, Miyake F.
Circ J. 2002 Dec;66(12):1101-4.

Relationship between infarction location and size to QT dispersion in patients with chronic myocardial infarction.

Hashimoto N, Musha H, Ozawa A, Imai Y, Kawasaki K, Miyazu O, Nagashima J, So T, Miyake F, Murayama M.
Jpn Heart J. 2002 Sep;43(5):455-61.

A case of coronary artery ectasia with thrombus detected by transthoracic two-dimensional echocardiography.

Hatano S, Nobuoka S, Tanaka H, Nagashima J, Ikeda K, Miyake F.
Echocardiography. 2002 Nov;19(8):693-4.

Determination of the target ventricular rate in patients with atrial fibrillation by evaluation of ventriculoarterial coupling.

Nobuoka S, Hatano S, Nagashima J, Yoshida A, Adachi H, Imai Y, Shibamoto M, Ikeda K, Miyake F.
Tex Heart Inst J. 2002;29(2):100-4.
2001年

Assessment of reflection pulse wave in patients with cardiomyopathy: evaluation of noninvasive measurement of wave intensity.

Nobuoka S, Aono J, Nagashima J, Ando H, Adachi H, Imai Y, Shibamoto M, Tanaka H, Miyake F, Murayama M.
Acta Cardiol. 2001 Oct;56(5):283-7

Spatial and temporal analysis of left ventricular filling flow propagation in hypertensive patients before and after regression of myocardial hypertrophy with alacepril therapy.

Nobuoka S, Nagashima J, Hatano S, Fujimaki R, Saito K, Tokuoka S, Ando H, Miyake F.Echocardiography. 2001 Aug;18(6):479-83.

Effects of prolonged strenuous exercise on plasma levels of atrial natriuretic peptide and brain natriuretic peptide in healthy men.

Ohba H, Takada H, Musha H, Nagashima J, Mori N, Awaya T, Omiya K, Murayama M.
Am Heart J. 2001 May;141(5):751-8.

Congenital giant aneurysm of the left atrial appendage mimicking pericardial absence case report.

Kunishima T, Musha H, Yamamoto T, Aoyagi H, Kongoji K, Imai M, Ozawa A, So T, Nagashima J, Murayama M.
Jpn Circ J. 2001 Jan;65(1):56-9.
2001年

Influence of angiotensin-converting enzyme gene polymorphism on development of athlete's heart.

Nagashima J, Musha H, Takada H, Awaya T, Oba H, Mori N, Ohmiya K, Nobuoka S, Murayama M.
Clin Cardiol. 2000 Aug;23(8):621-4.
[Preparticipation physical examination to sports for the patients with the internal medicine].

Nagashima J
, Murayama M, Musha H.
Nippon Rinsho. 2000 Sep;58 Suppl:110-4. Review. Japanese. No abstract available.

[Cardiac amyloidosis].

Nobuoka S, Hatano S, Nagashima J, Miyake F.
Nippon Rinsho. 2000 Jan;58(1):177-80. Review. Japanese.
1999年

Effect of angiotensin-converting enzyme gene polymorphism on left ventricular remodeling after anteroseptal infarction.

Nagashima J, Musha H, So T, Kunishima T, Nobuoka S, Murayama M.
Clin Cardiol. 1999 Sep;22(9):587-90.
1998年
Myocardial Injury After an Ultramarathon: Echocardiographic Assessment During Isometric Exercise and Serum Cardiac Troponin T Level.

Nagashima J
, Musha H, Takada H, Ohmiya K, Awaya T, Oba H, Nobuoka S, Murayama M.
Int J Sport Cardiol  1999 8(2)77-82.
Acute myocardial infarction induced by alternating exposure to heat in a sauna and rapid cooling in cold water.

Imai Y, Nobuoka S, Nagashima J, Awaya T, Aono J, Miyake F, Murayma M.
Cardiology. 1998;90(4):299-301.
[Assessment of localized hypertrophy in the basal part of the interventricular septum in the elderly].

Nobuoka S, Nagashima J, Fujimaki R, Sugihara H, Imai Y, Sakakibara M, Miyake F, Murayama M.

Nippon Ronen Igakkai Zasshi. 1998 Sep;35(9):686-90. Japanese.
Beneficial effects of mechanical reperfusion therapy on left ventricular remodeling and late outcome following myocardial infarction.

Sakakibara M, Tochiki H, Sasaki T, Kunishima T, Nagashima J, Miyake F, Murayama M.

Jpn Heart J. 1998 Jul;39(4):419-33.
Heart failure in 3 patients with acromegaly: echocardiographic assessment.

Aono J, Nobuoka S, Nagashima J, Hatano S, Yoshida A, Ando H, Miyake F, Murayama M.
Intern Med. 1998 Jul;37(7):599-603.